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The Biggest Public Health Crisis of 21st Century When e-cigarettes or vaping devices were first introduced to the American market back in 2007, they were hailed as the “safe” new alternative to smoking traditional cigarettes, which is why vaping, as an idea, quickly gained popularity among adults trying to kick the habit

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[83] Nicotine also stimulates nicotinic acetylcholine receptors in the adrenal medulla, resulting in increased levels of epinephrine and beta-endorphin